Phase: |
Workpackage |
Theme: | Technology for Prevention and Reduction of Disease and Disability (WP5 TECH-DD) |
Type: | Research |
Status: | Ended |
Start Date: | 2016-05-30 |
End Date: | 2018-01-31 |
Project Leaders |
John, Sasha Yoo, Paul |
Project Overview
Overactive bladder (OAB) is an incurable urinary disorder that affects 18% of Canadian adults. Successful treatment can improve quality of life by alleviating anxiety, social withdrawal, depression, and preventing falls that come about when people urgently seek the bathroom. Current treatment options for OAB (and limitations) include: (a) pharmaceuticals (poor patient compliance/side effects); (b) spinal nerve stimulation (expensive and invasive implantable device); and (c) tibial nerve stimulation therapy (requires ongoing clinic-based treatment). The overall clinical efficacy of these therapies is notably limited. We have recently discovered a new nerve stimulation target that may provide improved treatment of OAB. Our goal is to show improved therapeutic benefit in patients with this novel treatment. The successful completion of this project will allow the introduction of new types of implantable devices and clinic-based treatments.
New therapy for overactive bladder
Outputs
Title |
Category |
Date |
Authors |
A pilot feasibility study of treating overactive bladder patients with percutaneous saphenous nerve stimulation.Peer-reviewed journal publication that reports the results from our first pilot clinical study that assessed the therapeutic effects of percutaneous saphenous nerve stimulation. University of Toronto | Scientific Excellence - Advancing Knowledge | 2018-03-02 | "Scott MacDiarmid", Sasha John, Paul Yoo |
PERCUTANEOUS STIMULATION OF THE SAPHENOUS NERVE: A NOVEL EXPERIMENTAL APPROACH TO TREATING OVERACTIVE BLADDER.Pilot clinical study of saphenous nerve stimulation University of Toronto | Scientific Excellence - Advancing Knowledge | 2018-03-02 | "Scott MacDiarmid", Sasha John, Paul Yoo |